{"id":3739,"date":"2023-07-21T09:57:55","date_gmt":"2023-07-21T16:57:55","guid":{"rendered":"https:\/\/grail.com\/?page_id=3739"},"modified":"2025-09-25T14:45:59","modified_gmt":"2025-09-25T21:45:59","slug":"biopharma-partnerships","status":"publish","type":"page","link":"https:\/\/grail.com\/biopharma-partnerships\/","title":{"rendered":"Biopharma Partnerships"},"content":{"rendered":"\n\n<div class=\"hero-two-columns grail-block\">\n    <div class=\"grid-container\">\n        <div class=\"grid-x hero-container to-left\">\n            <div class=\"cell small-12 large-6 flex-container container-image to-left \">\n                <div class=\"image-wrapper \">\n                    <img decoding=\"async\" class=\"image animate--stagger-in small-order-1 align-left medium-order-0\" src=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2022\/06\/Screenshot-2025-09-09-at-4.16.23%E2%80%AFPM.png\" alt=\"grail scientist cancer detection\">\n                <\/div>\n                <div class=\"figure-svg show-for-xxlarge medium-order-1\">\n                    <img decoding=\"async\" class=\"image-svg bottom-section \" src=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2020\/12\/partner-svg.svg\" alt=\"Background texture\">\n                <\/div>\n                <div class=\"figure-svg show-for-medium-down\">\n                    <img decoding=\"async\" class=\"image-svg bottom-section \" src=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2020\/11\/svgHero.svg\" alt=\"Background texture\">\n                <\/div>\n            <\/div>\n            <div class=\"cell small-12 medium-order-0 container-text animate--fade-in style-one large-6 \">\n                                    <img decoding=\"async\" class=\"logo\" src=\"\" alt=\"\">\n                                <h2 class=\"heading heading-2 title\">Biopharma Partnerships<\/h2>\n                                    <div class=\"text-description\">\n                        <p>Advancing novel cancer therapeutics through next generation liquid biopsy solutions.<\/p>\n<p><strong>Our Pharma Partnership Makes It Possible\u00a0<\/strong><br \/>\nWe help our pharma partners accelerate precision oncology across cancer indications and therapeutic modalities with research to clinical trials and ultimately, registration and commercial launch.<\/p>\n<p>Our team brings together biopharma and companion diagnostics expertise with biomarker, drug-diagnostic co-development, and commercialization experience.<\/p>\n<p>Our pharma partnerships deliver cancer detection, classification, and quantification results with the potential to analyze and monitor epigenetic signatures from early to advanced stage cancer.<\/p>\n<p>Data from GRAIL studies have demonstrated analytically validated performance<sup>1<\/sup> with robust analytical sensitivity, specificity, and precision.<\/p>\n<p>We leverage the combination of GRAIL\u2019s proprietary methylation-based multi-cancer early detection (MCED) liquid biopsy platform and biologically motivated machine learning capabilities.<\/p>\n                    <\/div>\n                                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer base-block\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading base-block\">GRAIL Cancer Research Solution : a multi-cancer ctDNA toolkit for biopharma research and clinical testing<\/h2>\n\n\n\n<p class=\"base-block\">GRAIL&#8217;s Cancer Research Solution is a blood-only ctDNA platform for sensitive and specific cancer detection, with the aim to advance precision cancer care. With one tube of blood, the test analyzes more than a million CpGs identified through population-scale clinical studies<sup>2,3<\/sup> and leverages machine learning classifiers to detect, classify, and quantify ctDNA<sup>4<\/sup>.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading base-block\">GRAIL&#8217;s Tissue-free Platform to Support Precision Cancer Care<\/h4>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;690de6f896a27&quot;}\" data-wp-interactive=\"core\/image\" class=\"wp-block-image size-large is-resized base-block wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"461\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on-async--click=\"actions.showLightbox\" data-wp-on-async--load=\"callbacks.setButtonStyles\" data-wp-on-async-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma1-2-1024x461.png\" alt=\"\" class=\"wp-image-5566\" style=\"width:630px;height:auto\" srcset=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma1-2-1024x461.png 1024w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma1-2-300x135.png 300w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma1-2-768x346.png 768w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma1-2-1536x692.png 1536w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma1-2-2048x923.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on-async--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n\n\n\n<p class=\"base-block\"><\/p>\n\n\n\n<p class=\"base-block\"><\/p>\n\n\n\n<h4 class=\"wp-block-heading base-block\">Potential Applications Across the Cancer Care Continuum<\/h4>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;690de6f896dec&quot;}\" data-wp-interactive=\"core\/image\" class=\"wp-block-image size-large is-resized base-block wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"439\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on-async--click=\"actions.showLightbox\" data-wp-on-async--load=\"callbacks.setButtonStyles\" data-wp-on-async-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma2-1024x439.png\" alt=\"\" class=\"wp-image-5562\" style=\"width:630px\" srcset=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma2-1024x439.png 1024w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma2-300x129.png 300w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma2-768x329.png 768w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma2-1536x658.png 1536w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma2-2048x878.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on-async--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n\n\n\n<p class=\"base-block\"><\/p>\n\n\n\n<p class=\"base-block\">This enables ctDNA applications spanning from exploratory research and biomarker studies to clinical trial stratification and selection. GRAIL\u2019s Cancer Research Solution and tunable machine learning architecture are poised to support novel biopharma precision oncology strategies.<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer base-block\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading base-block\">Applications and Key Publications<\/h2>\n\n\n\n<section class=\"accordion-text js-tabber grail-block\">\n  <div class=\"accordion-text__container\">\n    <div class=\"accordion-text__tabs\">\n                      <button class=\"accordion-text__tab js-tab --active\">Detection<\/button>\n                              <button class=\"accordion-text__tab js-tab \">Classification<\/button>\n                              <button class=\"accordion-text__tab js-tab \">Quantification<\/button>\n                  <\/div>\n\n    <div class=\"accordion-text__tab-content-wrapper js-accordion\">\n                      <section class=\"accordion-text__tab-content js-tab-content --active\">\n          <div class=\"accordion-text__tab-content-heading\">Detection<\/div>\n          <div class=\"accordion-text__tab-content-container\">\n            <div class=\"accordion-text__tab-content-text\"><p>Detection before, during, or after treatment for risk stratification, patient selection, and minimal residual disease (MRD) assessment:<\/p>\n<ul>\n<li>Circulating tumor DNA (ctDNA) dynamics and treatment responses in chemotherapy-ineligible patients (pts) with unresectable stage III NSCLC from the phase II DUART trial. <em>Ann Oncolology <\/em><strong>2024<\/strong>. <strong><a href=\"https:\/\/www.annalsofoncology.org\/article\/S0923-7534(24)03872-9\/fulltext\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\">Abstract<\/span><\/a> \/ <a href=\"https:\/\/oncologycongressresource.com\/e0wo24?utm_term=QR&amp;utm_medium=Poster&amp;utm_campaign=ESMO&amp;utm_content=Circulating-tumor-DNA-dynamics-and-treatment-responses-in-chemotherapy-ineligible-patients-with-unresectable-Stage-III-NSCLC-from-the-phase-2-DUART-trial&amp;utm_source=&amp;utm_contentcategory=Translational\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\">Slides<\/span><\/a><\/strong><\/li>\n<li>Circulating Tumor DNA (ctDNA) Clearance With Neoadjuvant Durvalumab (D) + Tremelimumab (T) + Enfortumab Vedotin (EV) for Cisplatin-Ineligible Muscle Invasive Bladder Cancer (MIBC) From the Safety Run-In Cohort of the Phase 3 VOLGA Trial. <em>Ann Oncology <\/em><strong>2024<\/strong>. <strong><a href=\"https:\/\/www.annalsofoncology.org\/article\/S0923-7534(24)03574-9\/fulltext\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\">Abstract<\/span><\/a> \/ <a href=\"https:\/\/oncologycongressresource.com\/op2kkq?utm_term=QR&amp;utm_medium=Poster&amp;utm_campaign=ESMO&amp;utm_content=Circulating-Tumor-DNA-ctDNA-Clearance-With-Neoadjuvant-Durvalumab-D-+-Tremelimumab-T-+-Enfortumab-Vedotin-EV-for-Cisplatin-Ineligible-Muscle-Invasive-Bladder-Cancer-MIBC-From-the-Safety-Run-In-Cohort-of-the-Phase-3-VOLGA-Trial&amp;utm_source=&amp;utm_contentcategory=Primary%20clinical\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\">Slides<\/span><\/a><\/strong><\/li>\n<li>Clinical Utility of Tumor-Na\u00efve Pre-surgical ctDNA Detection in Early-stage NSCLC. <em>Journal of Thoracic Oncology <\/em><strong>2024<\/strong>. <a href=\"https:\/\/www.jto.org\/article\/S1556-0864(24)00666-X\/fulltext\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\"><strong>Manuscript<\/strong><\/span><\/a><\/li>\n<\/ul>\n<\/div>\n                      <\/div>\n        <\/section>\n                              <section class=\"accordion-text__tab-content js-tab-content \">\n          <div class=\"accordion-text__tab-content-heading\">Classification<\/div>\n          <div class=\"accordion-text__tab-content-container\">\n            <div class=\"accordion-text__tab-content-text\"><p>Classification utilizing methylation signatures to determine cancer signal origin, cancer subtypes or predictive signatures for precision therapies:<\/p>\n<ul>\n<li>Identification of cancer subtypes with a ctDNA-based targeted methylation assay. <em>Cancer Research <\/em><strong>2024<\/strong>. <span style=\"text-decoration: underline;\"><a href=\"https:\/\/aacrjournals.org\/cancerres\/article\/84\/6_Supplement\/7566\/741492\/Abstract-7566-Identification-of-cancer-subtypes\" target=\"_blank\" rel=\"noopener\"><b>Abstract<\/b><\/a><\/span><b> \/ <\/b><span style=\"text-decoration: underline;\"><a href=\"\/wp-content\/uploads\/2024\/04\/7566_Nance_AACR-2024-PDx-Disease-Subtyping_Poster_Final.pdf\" target=\"_blank\" rel=\"noopener\"><b>Poster<\/b><\/a><\/span><\/li>\n<li>Utility of ctDNA-based Targeted Methylation MRD Assay for Hematological Malignancies. <em>Cancer Research <\/em><strong>2023<\/strong>. <span style=\"text-decoration: underline;\"><a href=\"https:\/\/aacrjournals.org\/cancerres\/article\/83\/7_Supplement\/3369\/719441\/Abstract-3369-Utility-of-ctDNA-based-targeted\" target=\"_blank\" rel=\"noopener\"><b>Abstract<\/b><\/a><\/span><b> \/ <\/b><span style=\"text-decoration: underline;\"><a href=\"\/wp-content\/uploads\/2023\/05\/AACR-2023-GRAIL-Poster-12APR2023_FINAL.pdf\" target=\"_blank\" rel=\"noopener\"><b>Poster<\/b><\/a><\/span><\/li>\n<li>cfDNA methylation profiling distinguishes lineage-specific hematologic malignancies. <em>Cancer Research <\/em><strong>2020.<\/strong> <span style=\"text-decoration: underline;\"><a href=\"https:\/\/aacrjournals.org\/cancerres\/article\/80\/16_Supplement\/139\/641320\/Abstract-139-cfDNA-methylation-profiling\" target=\"_blank\" rel=\"noopener\"><b>Abstract <\/b><\/a><\/span><b>\/ <\/b><span style=\"text-decoration: underline;\"><a href=\"\/wp-content\/uploads\/2020\/12\/AACR_2020_Liu_Heme_POS_Final.pdf\" target=\"_blank\" rel=\"noopener\"><b>Poster<\/b><\/a><\/span><\/li>\n<\/ul>\n<\/div>\n                      <\/div>\n        <\/section>\n                              <section class=\"accordion-text__tab-content js-tab-content \">\n          <div class=\"accordion-text__tab-content-heading\">Quantification<\/div>\n          <div class=\"accordion-text__tab-content-container\">\n            <div class=\"accordion-text__tab-content-text\"><p>Quantification to determine disease burden and molecular response as surrogate for treatment efficacy:<\/p>\n<ul>\n<li>A Novel Tissue-Free Method to Estimate Tumor-Derived Cell-Free DNA Quantity Using Tumor Methylation Patterns. <em>Cancers <\/em><strong>2024<\/strong>. <span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.mdpi.com\/2072-6694\/16\/1\/82\" target=\"_blank\" rel=\"noopener\"><b>Manuscript<\/b><\/a><\/span><\/li>\n<li>Prognostic significance of blood-based multi-cancer detection in plasma cell-free DNA. <em>Clinical Cancer Research <\/em><strong>2021<\/strong>. <span style=\"text-decoration: underline;\"><a href=\"https:\/\/aacrjournals.org\/clincancerres\/article\/27\/15\/4221\/671557\/Prognostic-Significance-of-Blood-Based-Multi\" target=\"_blank\" rel=\"noopener\"><b>Manuscript<\/b><\/a><\/span><\/li>\n<li>Circulating Tumor DNA Allele Fraction: A Candidate Biological Signal for Multi-Cancer Early Detection Tests to Assess the Clinical Significance of Cancers. <em>The American Journal of Pathology <\/em><strong>2022<\/strong>. <span style=\"text-decoration: underline;\"><a href=\"https:\/\/ajp.amjpathol.org\/article\/S0002-9440(22)00211-5\/fulltext\" target=\"_blank\" rel=\"noopener\"><b>Manuscript<\/b><\/a><\/span><\/li>\n<\/ul>\n<\/div>\n                      <\/div>\n        <\/section>\n                  <\/div>\n<\/section>\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer base-block\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading base-block\">Regulatory and Clinical Trial Capabilities<\/h2>\n\n\n\n<p class=\"base-block\">Currently the GRAIL ctDNA assay is being used in global Phase 3 clinical studies such as [<a href=\"https:\/\/clinicaltrials.gov\/search?cond=NCT06564844\">NCT06564844<\/a>]. <a href=\"https:\/\/grail.com\/press-releases\/grail-announces-first-patient-tested-with-blood-based-assay-in-global-phase-3-adjuvant-lung-cancer-study\/\"><strong>Read More<\/strong><\/a>. GRAIL brings extensive<em> in vitro<\/em> diagnostics (IVD) development and regulatory experience as well as needed certifications to ensure international regulatory compliance. <\/p>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;690de6f897943&quot;}\" data-wp-interactive=\"core\/image\" class=\"wp-block-image size-large is-resized base-block wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"432\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on-async--click=\"actions.showLightbox\" data-wp-on-async--load=\"callbacks.setButtonStyles\" data-wp-on-async-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma3-1024x432.png\" alt=\"\" class=\"wp-image-5578\" style=\"width:630px\" srcset=\"https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma3-1024x432.png 1024w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma3-300x127.png 300w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma3-768x324.png 768w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma3-1536x648.png 1536w, https:\/\/assets.grail.com\/wp-content\/uploads\/2025\/01\/biopharma3-2048x864.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on-async--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><\/figure>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer base-block\"><\/div>\n\n\n\n<a name=\"biopharmacontact\" id=\"biopharmacontact\" class=\"base-block\"><\/a>\n\n\n    <div class=\"overlapping-background-text-cta to-left grail-block\">\n        <div class=\"grid-container\">\n            <div class=\"grid-x\">\n                <div class=\"cell medium-9  cell-article normal\">\n                    <div class=\"content animate--fade-in\" id=\"biopharma-partnershipss\">\n                                                    \n                            <div class=\"row\">\n                                <h2 class=\"heading heading-2\">Contact the Biopharma Partnership Team<\/h2>\n                                                                    <div class=\"paragraphs\">\n                                        <p>Partner with GRAIL for your oncology diagnostic testing needs across biomarker discovery, retrospective studies and companion diagnostic tests to accelerate your efforts to bring impactful solutions.<\/p>\n<p>Contact us by filling out the following form, and our team will get in touch:<\/p>\n<style>\n.wpcf7 .wpcf7-select,.wpcf7 input {<br \/>\n    padding: 0;<br \/>\n    width: 100%;<br \/>\n    height: auto;<br \/>\n    color: #6a4d2f;<br \/>\n    font-size: 3rem;<br \/>\n    margin-top: 5px;<br \/>\n    margin-bottom: 5px;<br \/>\n    box-shadow: none;<br \/>    font-family: \"DM Serif Display\",sans-serif;<br \/>\n    border: none;<br \/>\n    border-bottom: 1px solid #92704d;<br \/>\n}<br \/>\n<\/style>\n\n<div class=\"wpcf7 no-js\" id=\"wpcf7-f4666-o1\" lang=\"en-US\" dir=\"ltr\" data-wpcf7-id=\"4666\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/wp-json\/wp\/v2\/pages\/3739#wpcf7-f4666-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"Contact form\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"4666\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.2\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"en_US\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f4666-o1\" \/><input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/><input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/><input type=\"hidden\" name=\"_wpcf7_recaptcha_response\" value=\"\" \/>\n<\/fieldset>\n<p><label>Full Name: <span class=\"wpcf7-form-control-wrap\" data-name=\"your-name\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" autocomplete=\"name\" aria-required=\"true\" aria-invalid=\"false\" value=\"\" type=\"text\" name=\"your-name\" \/><\/span><\/label><br \/>\n<label>Organization:<span class=\"wpcf7-form-control-wrap\" data-name=\"your-organization\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" autocomplete=\"company\" aria-required=\"true\" aria-invalid=\"false\" value=\"\" type=\"text\" name=\"your-organization\" \/><\/span><\/label><br \/>\n<label>Position at the Organization: <span class=\"wpcf7-form-control-wrap\" data-name=\"your-position\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" value=\"\" type=\"text\" name=\"your-position\" \/><\/span><\/label><br \/>\n<label>Email address: <span class=\"wpcf7-form-control-wrap\" data-name=\"your-email\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-email wpcf7-validates-as-required wpcf7-text wpcf7-validates-as-email\" autocomplete=\"email\" aria-required=\"true\" aria-invalid=\"false\" value=\"\" type=\"email\" name=\"your-email\" \/><\/span><\/label><br \/>\n<label>How can we assist you? <span class=\"wpcf7-form-control-wrap\" data-name=\"your-message\"><textarea cols=\"40\" rows=\"10\" maxlength=\"2000\" class=\"wpcf7-form-control wpcf7-textarea wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" name=\"your-message\"><\/textarea><\/span><\/label>\n<\/p>\n<p><input class=\"wpcf7-form-control wpcf7-submit has-spinner\" type=\"submit\" value=\"Submit\" \/>\n<\/p><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n\n                                    <\/div>\n                                                                                            <\/div>\n                                            <\/div>\n                <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n\n\n\n\n<div class=\"text-with-cta animate--fade-in info-container grail-block\">\n    <p class=\"heading heading-2 title\">Laboratory\/test information<\/p>\n    <p class=\"description\"><p>GRAIL\u2019s clinical laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and accredited by the College of American Pathologists. GRAIL\u2019s clinical laboratory is regulated under CLIA to perform high-complexity testing. The RUO test was developed, and its performance characteristics were determined by GRAIL. The RUO test is For Research Use Only, Not for Diagnostic Procedures. GRAIL&#8217;s RUO product offerings have not been cleared or approved by the Food and Drug Administration.<\/p>\n<\/p>\n    <\/div>\n\n\n\n<div class=\"text-with-cta animate--fade-in info-container grail-block\">\n    <p class=\"heading heading-2 title\">References<\/p>\n    <p class=\"description\"><p><sub>1. Desai M, et al. Analytical validation of a tissue-free, multi-cancer, post- diagnosis cancer research test that uses cell-free DNA methylation profiling (LB297). American Association for Cancer Research (AACR) Annual Meeting, April 14-19, 2023, Orlando, Florida.<\/sub><br \/>\n<sub>2. Liu MC, Oxnard GR, Klein EA, Swanton C, Seiden MV. Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA. Ann Oncol. 2020;31(6):745-759. doi:10.1016\/j.annonc.2020.02.011.<\/sub><br \/>\n<sub>3. Jamshidi A, Liu MC, Klein EA, et al. Evaluation of cell-free DNA approaches for multi-cancer early detection. Cancer Cell. 2022;40(12):1537-1549.e12. doi: 10.1016\/j.ccell.2022.10.022.<\/sub><br \/>\n<sub>4. Melton CA, Freese P, Zhou Y, et al. A Novel Tissue-Free Method to Estimate Tumor-Derived Cell-Free DNA Quantity Using Tumor<\/sub><\/p>\n<\/p>\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>GRAIL Cancer Research Solution : a multi-cancer ctDNA toolkit for biopharma research and clinical testing GRAIL&#8217;s Cancer Research Solution is a blood-only ctDNA platform for sensitive and specific cancer detection, with the aim to advance precision cancer care. With one tube of blood, the test analyzes more than a million CpGs identified through population-scale clinical [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-3739","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Biopharma Partnerships - GRAIL<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/grail.com\/biopharma-partnerships\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Biopharma Partnerships - GRAIL\" \/>\n<meta property=\"og:description\" content=\"GRAIL Cancer Research Solution : a multi-cancer ctDNA toolkit for biopharma research and clinical testing GRAIL&#8217;s Cancer Research Solution is a blood-only ctDNA platform for sensitive and specific cancer detection, with the aim to advance precision cancer care. 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